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39岁的布伦南•哈夫（威尔•法瑞尔 Will Ferrell 饰）无业，一直在母亲南希（玛丽•斯汀伯根 Mary Steenburgen 饰）家蹭吃蹭住。40岁的戴尔•多巴克（约翰•赖利 John Reilly 饰）也是个与父亲罗伯特（理查德•詹金斯 Richard Jenkins 饰）住在一起的大龄男，靠父亲的接济生活。南希与罗伯特一见钟情，婚后搬入罗伯特家居住，布伦南也随母亲一起搬入，从此被迫以继兄弟的身份与戴尔同处一室。二人从相互敌视逐渐成为最佳拍档，共同对付布伦南的优秀弟弟德里克（亚当•斯科特 Adam Scott 饰），玩闹得不亦乐乎。可没想到他们的胡作非为却毁了父母刚建立起来的美满婚姻，二人后悔万分，终于决定痛改前非……。贫民窟归来的真少爷江尘，在江家受尽屈辱！家人宠爱养子江北，母亲跟三位姐姐也偏袒养子！被污蔑泄露机密后，江尘心灰意冷，割掌断亲！。Life in the Catholic Church of the Holy Redeemer in Detroit is upset by a series of killings whose victims are all priests and nuns. All victims are found with a black rosary in their hands. Father Koesler begins collaborating with the police but soon finds himself in a spot when the killer decides to choose him as confessor.。