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一群医学院实习医生某晚在医院附近酒吧玩乐时捉弄具有偷窥癖的医院清洁工肯尼斯（安德鲁-李•波茨 Andrew-Lee Potts 饰），并戏虐他为“疯狗”。被逼饮酒过量的肯尼斯癫痫发作昏厥，成为植物人，就要被终止治疗实施安乐死。倍感内疚的实习医生凯萨琳（阿莉尔•凯贝尔 Arielle Kebbel 饰）违反章程给肯尼斯注射了某种还在实验阶段的混合药物，试图让肯尼斯尽早苏醒，却没想到药物竟促成了肯尼斯灵魂出窍，附体到他人身上开始残忍的复仇行动。等到凯萨琳察觉出问题所在，却为时已晚，肯尼斯的灵魂早已脱离掌控，不管是陌生人还是朋友，甚至包括自己，凯萨琳还能相信谁？。A dentist teams up with a feisty would-be assassin to put the final touches on the plan to kill his wife. Once he makes a play for the assassin's payment, he unknowingly sets off a chain of events that fuels a cross-town journey through the many lounges, bars, strip clubs and the occasional nudist ping pong club scattered across Los Angeles. Along the way, we are introduced to ...。桑晚意跟陆临渊结婚三年，关系一直不痛不痒，直到陆临渊的初恋白月光苏恩悦突然回国，陆临渊准备跟桑晚意离婚，桑晚意联合闺蜜开始捉奸，而直到准备离婚的这一刻陆临渊才发现自己从没了解过自己的老婆，二人离婚后他追悔莫及，开始追妻火葬场……。