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抗日战争英雄程怀远与农村姑娘水妹子相爱，他答应要在解放战争结束后回来娶水妹子。可当他再次来到插水村时，瘟疫在此蔓延，血吸虫病折磨着这里的乡亲们。程怀远任用李宋唐，组织血防队。为了发明新药，程怀远以身试药，差点送命。三日疗法成功后得到广泛应用，疫情缓解。吴忝绮对程怀远的敬仰遭到李宋唐的嫉妒，丧失理智的他污辱了水妹子。水妹子和程怀远在个人恩怨面前以大局为重，保全了李宋唐。血防工作状况频出，来怀沙治疗失误导致两个患者死亡，村民要求以命偿命。程怀远考虑到他的妻儿自己承担了责任，离开了血防队。水妹子嫁给了程怀远。程怀远创立的土埋法和开渠降水法很有成效。最后的攻坚阶段，程怀远回到灭螺前线，彻底消灭了血吸虫病。。It’s Easter 1967, and celebrations are underway for a colourful Easter bonnet parade outside Nonnatus House. Sister Monica Joan and Reggie are excited about the Eurovision song contest, while Cyril and Lucille settle into blissful married life. After taking some time away following the death of their newborn son, Derek and Audrey Fleming return to Poplar with good news - Audrey...。该剧改编自Gary L. Stewart撰写的同名畅销书，Stewart本人在寻找遗弃了自己的父亲时发现，他的父亲很可能就是逍遥法外、臭名昭著的连环杀手“十二宫杀手”。。