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医小满作为药老传承人被发现，遭凌家寻找。爷爷许春林离世后，许潇潇迫医小满。凌逸尘助其解围，医小满治其腿疾获凌家认可。许潇潇勾结傅星渊陷害医馆，被凌逸尘揭露阴谋。傅绑架三人，医小满智斗反派。最终傅、许受制裁，医小满上交药方，面临凌、叶求婚选择。Three years after the outbreak of an epidemic, three survivors have to make their way from a shelter in the thick of the woods to the city, in an attempt to save the world.。