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Lex (Anna Konkle) and Mani (Jermaine Fowler) are a happily married young couple, running their dream artisanal bakery in Los Angeles and excited about starting a family together. A trip to a tropical island resort for a friend’s destination wedding, coinciding with Lex’s ovulation cycle, feels like the perfect opportunity to conceive. But good vibes and high hopes are cut short...。一辆货车行驶在泥泞的乡间小路上，酒保保罗（马特·欧莱瑞 Matt O'Leary 饰）和派对组织者茱莉娅（Jessica Cook 饰）正前往他们的目的地，某个山间别墅。别墅所有人波奇妇人（Eve Slatner 饰）每年都会组织派对，请来至交亲朋共同缅怀她去世的丈夫。晴朗的午后，保罗他们有条不紊地布置会场，除了不知从何处而来的马蜂比较讨厌外，其他还都顺利。夜幕降临，宾客相继来到别墅庭院，大家共斟美酒，喜形于色。而就在此时，诡异疯狂的马蜂再次出现，它们肆无忌惮袭击在场的每个人，被袭击者受到感染，体内很快诞生出巨大的马蜂怪。 人们一个接一个倒下，而无情冷酷的杀手正向为数不多的幸存者们逼近……。